Publications

High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis.

Pradip A, Steel D, Jacobsson S, Holmgren G, Ingelman-Sundberg M, Sartipy P, Björquist P, Johansson I,  and Edsbagge J. Stem Cells International, Volume 2016, Article ID 2475631, 14 pages.

One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.

Asplund A, Pradip A, van Giezen M, Aspegren A, Choukair H, Rehnström M, Jacobsson S, Ghosheh N, El Hajjam D, Holmgren S, Larsson S, Benecke J, Butron M, Wigander A, Noaksson K, Sartipy P, Björquist P, Edsbagge J, Küppers-Munther B. Stem Cell Rev. 2015 Sep 19. PMID: 26385115

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.

Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, Björquist P, Widera A, Stöber R, Campos G, Hammad S, Sachinidis A, Chaudhari U, Damm G, Weiss TS, Nüssler A, Synnergren J, Edlund K, Küppers-Munther B, Hay DC, Hengstler JG. J Hepatol. 2015 Oct;63(4):934-42. doi: 10.1016/j.jhep.2015.05.013. Epub 2015 May 25. PMID: 26022688

Successful tissue engineering of competent allogeneic venous valves

Vijay Kumar Kuna, Antonio Rosales, Jonny Hisdal, Eivind K. Osnes, Jon O. Sundhagen, Henrik Bäckdahl, Suchitra Sumitran-Holgersson, Jørgen J. Jørgensen. Journal of Vascular Surgery: Venous and Lymphatic Disorders, Volume 3, Issue 4, Pages 421-430.e1 Mar 6, 2015

In Vivo Application of Tissue-Engineered Veins Using Autologous Peripheral Whole Blood: A Proof of Concept Study.

Olausson M, Kuna VK, Travnikova G, Bäckdahl H, Patil PB, Saalman R, Borg H, Jeppsson A, Sumitran-Holgersson S.

EBioMedicine. 2014 Sep 22;1(1):72-9. doi: 10.1016/j.ebiom.2014.09.001. eCollection 2014 Nov.

Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.

Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.

Holmgren G, Sjögren AK, Barragan I, Sabirsh A, Sartipy P, Synnergren J, Björquist P, Ingelman-Sundberg M, Andersson TB, Edsbagge J. Drug Metab Dispos. 2014 Sep;42(9):1401-6. doi: 10.1124/dmd.114.059154. Epub 2014 Jun 30.

Employment of the Triple Helix concept for development of regenerative medicine applications based on human pluripotent stem cells.

Sartipy P, Björquist P. Clin Transl Med. 2014 May 9;3:9. doi: 10.1186/2001-1326-3-9. eCollection 2014. Review.

Transplantation of an allogeneic vein bioengineered with autologous stem cells: a proof-of-concept study.

Olausson M, Patil PB, Kuna VK, Chougule P, Hernandez N, Methe K, Kullberg-Lindh C, Borg H, Ejnell H, Sumitran-Holgersson S. Lancet. 2012 Jul 21;380(9838):230-7. doi: 10.1016/S0140-6736(12)60633-3. Epub 2012 Jun 14.

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